Antibiotics Are Man's Greatest Invention

Month: June 2019

Genomic identification of cryptic susceptibility to penicillins and β-lactamase inhibitors in methicillin-resistant Staphylococcus aureus

Assessment of Nontraditional Products in Development to Combat Bacterial Infections

While antibiotic innovation—finding and designing new types of antibiotics and improving existing drugs—remains essential to combating antibiotic resistance, “outside-the-box” approaches to preventing and treating bacterial infections are also needed….

Pew Thanks Senators for Introducing Bill to Spur Antibiotic Development

The Pew Charitable Trusts sent a letter to Senators Bob Casey (D-PA) and Johnny Isakson (R-GA) on June 18 thanking them for introducing the Developing an Innovative Strategy for Antimicrobial Resistant Microorganisms (DISARM) Act of 2019….

A battle against antibiotic resistance

Outpatient Antibiotic Prescribing Varied Across the United States in 2016

The prescribing of antibiotics in outpatient health care facilities, such as primary care clinics and emergency rooms, represents a large proportion of antibiotic use in the United States….

Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes

Tracking the Global Pipeline of Antibiotics in Development

To shed light on the antibiotic pipeline, evaluate public policies, and monitor the potential impact on public health, The Pew Charitable Trusts has assessed antibiotics currently in clinical development….

American Civil War plant medicines inhibit growth, biofilm formation, and quorum sensing by multidrug-resistant bacteria

Fixing the Broken Antibiotic Market

On March 7, The Pew Charitable Trusts and the Infectious Diseases Society of America will co-sponsor a briefing on the need for economic incentives to spur the development of urgently needed new antibiotics. The event comes at the end of this year’s Stand Up to Superbugs fly-in and aims to inform congressional staff members about policies to reinvigorate the antibiotic pipeline….

Exploiting chitosan and gold nanoparticles for antimycobacterial activity of in silico identified antimicrobial motif of human neutrophil peptide-1